Translational Research

Tumorigenesis is a complex process driven by both genetic and metabolic alterations in neoplastic cells and the microenvironment surrounding these cells. Flow cytometry is an invaluable tool in further understanding the tumor immune microenvironment and the expanded research of minimal residual disease in cancer. BD Biosciences provides a variety of tools for research studies involving the immunophenotypic analysis of cancer cell populations.

The ability of the immune system to target cancer cells is driving studies in immuno-oncology and innovative targeted approaches in clinical research and therapy trials. It is proving critical to monitor immune responses in the tumor microenvironment to better understand response mechanisms and treatment resistance. Active immune monitoring is also useful for studying targeted therapy in allergy and autoimmunity. Autoimmune disorders such as rheumatoid arthritis and multiple sclerosis are characterized by alterations in specific immune cell populations over the progression and treatment of the disease. BD Biosciences provides a comprehensive portfolio of flow cytometry instruments and reagents for researching these complex processes.